DOI: https://dx.doi.org/10.18203/issn.2454-2156.IntJSciRep20223031
Published: 2022-11-23

Coronavirus disease 2019 vaccine acceptance, associated factors and perceived barriers among Dire Dawa university students, Ethiopia

Aminu Mohammed, Addisu Sertsu, Mickiale Hailu, Henok Legesse

Abstract


Background: Corona virus disease-2019 (COVID-19) is a family of severe acute respiratory infection first detected in 2019 in China. It has made high morbidity and mortality across the world. Currently, most countries including Ethiopia have taken preventive measures including vaccine. However, there is still limited evidence in COVID-19 vaccine acceptability and perceived barriers among some subgroups like university students. Therefore, this study was aimed to assess it and fill the information gap to enable intervention.

Methods: A cross-sectional study was conducted from April 01 to 30 2022 at Dire Dawa university and 337 students were selected using simple random sampling technique. Data was collected using structured, self-administered questionnaire, entered and cleaned by Epi DATA (Version 3.1) and analyzed using SPSS (Version 22). A p<0.2 at Bivarate to select variables for multivariable and <0.05 at multivariable with 95% CI was considered as statistical significance.  

Results: COVID-19 vaccine acceptance was 26.7% (95% CI: 22-31.5%). Urban resident (AOR: 3.13, CI: 1.61-6.10), mothers’ education (AOR: 3.48, CI: 1.44-8.43), knowledge (AOR: 2.23, CI: 1.21-4.11) and favorable intention towards COVID-19 prevention (AOR: 2.21, CI: 1.11-4.38) were independent factors associated with COVID-19 vaccine acceptance.

Conclusions: COVID-19 vaccine acceptance was lower than national average in Ethiopia. The predictors were residence, mothers’ education, knowledge and intention towards COVID-19 prevention. Major barriers were misconceptions, uncertainty on effectiveness, concern on side effects and a need to know more about the vaccine. Integrated health education campaign on vaccine’s misconception was recommended. 


Keywords


COVID-19 vaccine, Acceptance, Associated factors, Barriers, Students

Full Text:

PDF

References


Wu D, Wu T, Liu Q, Yang Z. The SARS-CoV-2 outbreak: what we know. Int J Infect Dis. 2020;94:44-8.

Zumla A, Hui DS, Perlman S. Middle East respiratory syndrome. Lancet. 2015;386(9997):995-1007.

Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401-2.

Ong SWX, Tan YK, Chia PY, Lee TH, Ng OT, Wong MSY et al. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA. 2020;323(16):1610-2.

Lewis D. Is the coronavirus airborne? Experts can’t agree. Nature. 2020;580(7802):175.

Morawska L, Cao J. Airborne transmission of SARS-CoV-2: The world should face the reality. Environment Int. 2020;139:105730.

Struyf T, Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MM et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 disease. Cochrane Database of Systematic Rev. 2020;7(7):CD013665.

Organization WH. Coronavirus disease (‎‎ COVID-19)‎‎: situation Report. 2020;166.

Behzad S, Aghaghazvini L, Radmard AR, Gholamrezanezhad A. Extrapulmonary manifestations of COVID-19: Radiologic and clinical overview. Clin Imag. 2020;66:35–41.

Li HY, Cao H, Leung DY, Mak YW. The psychological impacts of a COVID-19 outbreak on college students in China: a longitudinal study. Int J Environmental Res Public Heal. 2020;17(11):3933.

Son C, Hegde S, Smith A, Wang X, Sasangohar F. Effects of COVID-19 on college students’ mental health in the United States: Interview survey study. J Med Internet Res. 2020;22(9):e21279.

Bettinsoli ML, Di Riso D, Napier JL, Moretti L, Bettinsoli P, Delmedico M et al. Psychological Impact and Contextual Factors Associated With Physical and Mental Health Conditions of Italian Healthcare Professionals During the COVID-19 Disease Outbreak. Appl Psychol Health Well Being. 2020;12(4):1054-73.

Li S, Wang Y, Xue J, Zhao N, Zhu T. The impact of COVID-19 epidemic declaration on psychological consequences: a study on active Weibo users. Int J Environmental Res Publ Heal. 2020;17(6):2032.

Jordan RE, Adab P, Cheng K. Covid-19: risk factors for severe disease and death. BMJ. 2020;368:m1198.

Lancet T. Redefining vulnerability in the era of COVID-19. Lancet (London, England). 2020;395(10230):1089.

Bradley NL, DiPasquale AM, Dillabough K, Schneider PS. Health care practitioners’ responsibility to address intimate partner violence related to the COVID-19 pandemic. CMAJ. 2020;192(22):E609-10.

Nepal R, Sapkota K, Adhikari K, Paudel P, Adhikari B, Paudyal N et al. Knowledge, attitude and practice regarding COVID-19 among healthcare workers in Chitwan, Nepal. J Chitwan Med College. 2020;10(3).

Olum R, Chekwech G, Wekha G, Nassozi DR, Bongomin F. Coronavirus disease-2019: knowledge, attitude, and practices of health care workers at Makerere University Teaching Hospitals, Uganda. Frontiers Publ Heal. 2020;8:181.

COVID-19 and violence against women: what the health sector/system can do, 7 April 2020. World Health Organization. 2020. Available at: https://apps.who.int/iris/handle/10665/331699. Accessed on 3 June 2022.

Roesch E, Amin A, Gupta J, García-Moreno C. Violence against women during covid-19 pandemic restrictions. Bri Med J Publish Group. 2020.

Williamson B, Eynon R, Potter J. Pandemic politics, pedagogies and practices: digital technologies and distance education during the coronavirus emergency. Taylor Francis. 2020.

Bozkurt A, Jung I, Xiao J, Vladimirschi V, Schuwer R, Egorov G et al. A global outlook to the interruption of education due to COVID-19 pandemic: Navigating in a time of uncertainty and crisis. Asian J Distance Educ. 2020;15(1):1-126.

Daniel Belema Fekene, Bulto GA, and BEM, Gemeda GM. Male Partner’s Involvement and it’s Associated Factors in Promoting Skilled Birth Attendance among Fathers who have Children Less than One Year of Age in Ambo Town, Ethiopia. EC Gynaecol. 2017;8.6(2019):465-74.

Arefi MF, Poursadeqiyan M. A review of studies on the epidemic crisis of COVID-19 disease with a preventive approach. Work. 2020(Preprint):1-13.

Sahu KK, Kumar R. Preventive and treatment strategies of COVID-19: From community to clinical trials. J Family Med Primary Care. 2020;9(5):2149.

Jemal B, Ferede ZA, Mola S, Hailu S, Abiy S, Wolde GD et al. Knowledge, attitude and practice of healthcare workers towards COVID-19 and its prevention in Ethiopia: a multicenter study. SAGE Open Med. 2020;9.

Aklil MB, Temesgan WZ. Knowledge and Attitude towards COVID-19 Vaccination and Associated Factors among College Students in Northwest Ethiopia, 2021. Heal Services Res Managerial Epidemiol. 2022;9:23333928221098903.

Baccolini V, Renzi E, Isonne C, Migliara G, Massimi A, De Vito C et al. COVID-19 Vaccine Hesitancy among Italian University Students: A Cross-Sectional Survey during the First Months of the Vaccination Campaign. Vaccines. 2021;9(11):1292.

Mose A, Haile K, Timerga A. COVID-19 vaccine hesitancy among medical and health science students attending Wolkite University in Ethiopia. PloS one. 2022;17(1):e0263081.

Patwary MM, Alam MA, Bardhan M, Disha AS, Haque MZ, Billah SM et al. COVID-19 Vaccine Acceptance among Low-and Lower-Middle-Income Countries: A Rapid Systematic Review and Meta-Analysis. Vaccines. 2022;10(3):427.

Raja SM, Osman ME, Musa AO, Hussien AA, Yusuf K. COVID-19 vaccine acceptance, hesitancy, and associated factors among medical students in Sudan. Plos one. 2022;17(4):e0266670.

Adane M, Ademas A, Kloos H. Knowledge, attitudes, and perceptions of COVID-19 vaccine and refusal to receive COVID-19 vaccine among healthcare workers in northeastern Ethiopia. BMC Publ Heal. 2022;22(1):1-14.

Ayele AD, Ayenew NT, Tenaw LA, Kassa BG, Yehuala ED, Aychew EW et al. Acceptance of COVID-19 vaccine and associated factors among health professionals working in Hospitals of South Gondar Zone, Northwest Ethiopia. Human Vaccines Immunotherap. 2021;17(12):4925-33.

Della Polla G, Pelullo CP, Di Giuseppe G, Angelillo IF. Changes in behaviors and attitudes in response to COVID-19 pandemic and vaccination in healthcare workers and university students in Italy. Vaccines. 2021;9(11):1276.

Shahwan M, Suliman A, Jairoun AA, Alkhoujah S, Al-Hemyari SS, Al-Tamimi SK et al. Prevalence, knowledge and potential determinants of COVID-19 vaccine acceptability among university students in the United Arab Emirates: findings and implications. J Multi Health. 2022;15:81.

Walker AN, Zhang T, Peng X-Q, Ge J-J, Gu H, You H. Vaccine acceptance and its influencing factors: an online cross-sectional study among international college students studying in China. Vaccines. 2021;9(6):585.

Szmyd B, Bartoszek A, Karuga FF, Staniecka K, Błaszczyk M, Radek M. Medical students and SARS-CoV-2 vaccination: attitude and behaviors. Vaccines. 2021;9(2):128.

Folcarelli L, Miraglia del Giudice G, Corea F, Angelillo IF. Intention to receive the COVID-19 vaccine booster dose in a university community in Italy. Vaccines. 2022;10(2):146.

Sugawara N, Yasui-Furukori N, Fukushima A, Shimoda K. Attitudes of Medical Students toward COVID-19 vaccination: Who is willing to receive a third dose of the vaccine? Vaccines. 2021;9(11):1295.

Kateeb E, Danadneh M, Pokorná A, Klugarová J, Abdulqader H, Klugar M et al. Predictors of willingness to receive COVID-19 vaccine: cross-sectional study of Palestinian dental students. Vaccines. 2021;9(9):954.

Mustapha M, Lawal BK, Sha’aban A, Jatau AI, Wada AS, Bala AA, et al. Factors associated with acceptance of COVID-19 vaccine among University health sciences students in Northwest Nigeria. PloS one. 2021;16(11):e0260672.

Riad A, Pokorná A, Antalová N, Krobot M, Zviadadze N, Serdiuk I, et al. Prevalence and drivers of COVID-19 vaccine hesitancy among Czech university students: National cross-sectional study. Vaccines. 2021;9(9):948.

Tavolacci MP, Dechelotte P, Ladner J. COVID-19 vaccine acceptance, hesitancy, and resistancy among university students in France. Vaccines. 2021;9(6):654.