Effect of dietary chitosan on the feed efficiency and weight performance of high fat diet induced hyperlipidemia in male wistar rat

Authors

  • Kunle Ogungbemi Nigerian Stored Products Research Institution, Federal Ministry of Agriculture and Rural Development.
  • Regina N. Ugbaja Department of Biochemistry, Federal University of Agriculture, Abeokuta, Ogun State
  • Funmilayo F. Ilesanmi Department of Chemistry/Biochemistry, Nigerian Stored Product Research Institute, Ibadan, Oyo State
  • Abolanle O. Ilori Department of Chemistry/Biochemistry, Nigerian Stored Product Research Institute, Ibadan, Oyo State
  • Toluwalope A. Odeniyi Department of Chemistry/Biochemistry, Nigerian Stored Product Research Institute, Ibadan, Oyo State
  • Boluwaji M. Adeniyi Department of Chemistry/Biochemistry, Nigerian Stored Product Research Institute, Ibadan, Oyo State
  • Daniel A. Balogun Department of Microbiology, Nigerian Stored Products Research Institute, Ilorin, Kwara State
  • Segun S. Ajisafe Department of Chemistry/Biochemistry, Nigerian Stored Product Research Institute, Ibadan, Oyo State

DOI:

https://doi.org/10.18203/issn.2454-2156.IntJSciRep20200645

Keywords:

Chitosan, Feed intake, Feed efficiency, Weight performance, Hyperlipidemia

Abstract

Background: This study was carried out to determine the growth performance of rats fed graded levels of chitosan supplemented High fat diet.  

Methods: Thirty male wistar rats weighing between 70 g and 90 g were purchased and randomly allotted into three (3) treatment groups with graded levels of chitosan in High fat diet (1%, 3% and 5%) and three (3) control groups namely: normal diet, High fat diet and normal diet +5% chitosan. The feed intakes as well as weight change of the experimental rats were monitored for six (6) weeks.

Results: The results obtained showed that the highest level of feed intake and feed efficiency were recorded for animals in group fed 5% level of chitosan supplementation when compared to other treatment groups. Similar result was observed for the weight change (as there was significant reduction in the weight gain with increase chitosan supplementation in HFD) which can be attributed to the efficient utilization of feed consumption.

Conclusions: It can be concluded that dietary chitosan prevents excess weight gain in hyperlipidemia and improves the overall nutritional attributes of the experimental diets by improving their feed efficiencies as compared to the control.

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Author Biography

Kunle Ogungbemi, Nigerian Stored Products Research Institution, Federal Ministry of Agriculture and Rural Development.

Department of Biochemistry/chemistry, NIgerian Stored Products Research Institute. (research Officer 1)

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Published

2020-02-25

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Original Research Articles